寺崎 美佳先生の破骨細胞型巨細胞を伴う子宮平滑筋肉腫の論文がVirchows ArchivにPublishされました!おめでとうございます!
Uterine leiomyosarcomas with osteoclast-like giant cells associated with high expression of RUNX2 and RANKL - Virchows Archiv
Uterine leiomyosarcoma (ULMS) with osteoclast-like giant cells (OLGCs) has been reported as a rare phenomenon in ULMS, and its clinico-pathological features and tumorigenesis remain unclear. We recently reported high expression of receptor activator of nuclear factor κB ligand (RANKL) in ULMS with OLGCs. As osteoblasts produce RANKL, in this study, we analyzed the expression of Runt-related transcription factor 2 (RUNX2), a critical transcription factor for osteoblasts, and osteoclast-related pr...