業績/論文

2020年

Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties.
Terashima Y, Toda E, Itakura M, Otsuji M, Yoshinaga S, Okumura K, Shand FHW, Komohara Y, Takeda M, Kokubo K, Chen MC, Yokoi S, Rokutan H, Kofuku Y, Ohnishi K, Ohira M, Iizasa T, Nakano H, Okabe T, Kojima H, Shimizu A, Kanegasaki S, Zhang MR, Shimada I, Nagase H, Terasawa H, Matsushima K.
Nat Commun. 2020 Jan 30;11(1):609. doi: 10.1038/s41467-020-14338-5. PMID: 32001710 [PubMed – in process]

Prolyl Hydroxylase Domain Inhibitor Protects against Metabolic Disorders and Associated Kidney Disease in Obese Type 2 Diabetic Mice.
Sugahara M, Tanaka S, Tanaka T, Saito H, Ishimoto Y, Wakashima T, Ueda M, Fukui K, Shimizu A, Inagi R, Yamauchi T, Kadowaki T, Nangaku M.
J Am Soc Nephrol. 2020 Mar;31(3):560-577. doi: 10.1681/ASN.2019060582. Epub 2020 Jan 29. PMID: 31996409 [PubMed – in process]

Agonistic anti-CD148 monoclonal antibody attenuates diabetic nephropathy in mice.
Takahashi K, Kim RH, Pasic L, He L, Nagasaka S, Katagiri D, May T, Shimizu A, Harris RC, Mernaugh RL, Takahashi T.
Am J Physiol Renal Physiol. 2020 Mar 1;318(3):F647-F659. doi: 10.1152/ajprenal.00288.2019. Epub 2020 Jan 27. PMID: 31984788 [PubMed – in process]

Immune checkpoint inhibitor-associated interstitial lung diseases correlate with better prognosis in patients with advanced non-small-cell lung cancer.
Sugano T, Seike M, Saito Y, Kashiwada T, Terasaki Y, Takano N, Hisakane K, Takahashi S, Tanaka T, Takeuchi S, Miyanaga A, Minegishi Y, Noro R, Kubota K, Gemma A.
Thorac Cancer. 2020 Feb 25. doi: 10.1111/1759-7714.13364. [Epub ahead of print] PMID: 32096610 

LPS-induced airway-centered inflammation leading to BOS-like airway remodeling distinct from RAS-like fibrosis in rat lung transplantation.
Takahagi A, Sato M, Chen-Yoshikawa TF, Miyamoto E, Saito M, Gochi F, Hamaji M, Yoshizawa A, Terasaki Y, Urushiyama H, Aoyama A, Sonobe M, Date H.
Transplantation. 2020 Jan 9. doi: 10.1097/TP.0000000000003097. [Epub ahead of print] PMID: 31929420

Cross-Talk between Transforming Growth Factor-β and Periostin Can Be Targeted for Pulmonary Fibrosis.
Nanri Y, Nunomura S, Terasaki Y, Yoshihara T, Hirano Y, Yokosaki Y, Yamaguchi Y, Feghali-Bostwick C, Ajito K, Murakami S, Conway SJ, Izuhara K.
Am J Respir Cell Mol Biol. 2020 Feb;62(2):204-216. doi: 10.1165/rcmb.2019-0245OC. PMID: 31505128

Epithelial Expression of YAP and TAZ Is Sequentially Required in Lung Development.
Isago H, Mitani A, Mikami Y, Horie M, Urushiyama H, Hamamoto R, Terasaki Y, Nagase T.
Am J Respir Cell Mol Biol. 2020 Feb;62(2):256-266. doi: 10.1165/rcmb.2019-0218OC. PMID: 31486675

2019年

Automated acquisition of explainable knowledge from unannotated histopathology images.
Yamamoto Y, Tsuzuki T, Akatsuka J, Ueki M, Morikawa H, Numata Y, Takahara T, Tsuyuki T, Tsutsumi K, Nakazawa R, Shimizu A, Maeda I, Tsuchiya S, Kanno H, Kondo Y, Fukumoto M, Tamiya G, Ueda N, Kimura G.
Nat Commun. 2019 Dec 18;10(1):5642. doi: 10.1038/s41467-019-13647-8. PMID: 31852890 [PubMed – indexed for MEDLINE]

Renal Complications after Hematopoietic Stem Cell Transplantation: Role of Graft-Versus-Host Disease in Renal Thrombotic Microangiopathy.
Mii A, Shimizu A, Yamaguchi H, Tsuruoka S.
J Nippon Med Sch. 2020 Mar 11;87(1):7-12. doi: 10.1272/jnms.JNMS.2020_87-102. Epub 2019 Nov 28. PMID: 31776318 [PubMed – in process]

Development of an organ bath technique for isolated rat pancreas preparations to assess the effect of 1,5-AG on insulin secretion.
Morita A, Ouchi M, Satoh K, Terada M, Kon H, Wakashin H, Hayashi K, Anzai N, Oba K, Shimizu A, Fujita T.
Exp Anim. 2019 Nov 15. doi: 10.1538/expanim.19-0059. [Epub ahead of print] PMID: 31735767 [PubMed – as supplied by publisher]

Human nephron number, hypertension, and renal pathology.
Kanzaki G, Tsuboi N, Shimizu A, Yokoo T.
Anat Rec (Hoboken). 2019 Nov 15. doi: 10.1002/ar.24302. [Epub ahead of print] PMID: 31729838 [PubMed – as supplied by publisher]

Bevacizumab-induced immunoglobulin A vasculitis with nephritis: A case report.
Endo Y, Negishi K, Hirayama K, Suzuki H, Shimizu A.
Medicine (Baltimore). 2019 Nov;98(45):e17870. doi: 10.1097/MD.0000000000017870. PMID: 31702653 [PubMed – indexed for MEDLINE]

Resection of Kommerell’s diverticulum in an infant with prenatal diagnosis of right aortic arch.
Suzuki K, Sasaki T, Kunugi S, Shima Y, Fukazawa R, Shimizu A, Nitta T.
Surg Case Rep. 2019 Nov 6;5(1):172. doi: 10.1186/s40792-019-0726-2. PMID: 31696330 [PubMed]

Illuminating Clues of Cancer Buried in Prostate MR Image: Deep Learning and Expert Approaches.
Akatsuka J, Yamamoto Y, Sekine T, Numata Y, Morikawa H, Tsutsumi K, Yanagi M, Endo Y, Takeda H, Hayashi T, Ueki M, Tamiya G, Maeda I, Fukumoto M, Shimizu A, Tsuzuki T, Kimura G, Kondo Y.
Biomolecules. 2019 Oct 30;9(11). pii: E673. doi: 10.3390/biom9110673. PMID: 31671711 [PubMed – in process]

Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits without Conspicuous Mesangial Proliferation, Complicated with Squamous Cell Lung Carcinoma.
Higashihara T, Okada A, Nakamura Y, Saigusa H, Homma S, Matsumura M, Kusano T, Shimizu A, Takano H.
Intern Med. 2020 Feb 15;59(4):557-562. doi: 10.2169/internalmedicine.2993-19. Epub 2019 Oct 15. PMID: 31611527 [PubMed – in process]

Estimation of nephron number in living humans by combining unenhanced computed tomography with biopsy-based stereology.
Sasaki T, Tsuboi N, Okabayashi Y, Haruhara K, Kanzaki G, Koike K, Kobayashi A, Yamamoto I, Takahashi S, Ninomiya T, Shimizu A, Rule AD, Bertram JF, Yokoo T.
Sci Rep. 2019 Oct 7;9(1):14400. doi: 10.1038/s41598-019-50529-x. PMID: 31591408 [PubMed – in process]

Intra-bone bone marrow transplantation from hCD47 transgenic pigs to baboons prolongs chimerism to >60 days and promotes increased porcine lung transplant survival.
Watanabe H, Ariyoshi Y, Pomposelli T, Takeuchi K, Ekanayake-Alper DK, Boyd LK, Arn SJ, Sahara H, Shimizu A, Ayares D, Lorber MI, Sykes M, Sachs DH, Yamada K.
Xenotransplantation. 2020 Jan;27(1):e12552. doi: 10.1111/xen.12552. Epub 2019 Sep 23. PMID: 31544995 [PubMed – in process]

A case of female Fabry disease revealed by renal biopsy.
Aratani S, Yamakawa H, Suzuki S, Otsuka T, Sakai Y, Shimizu A, Tsuruoka S.
CEN Case Rep. 2020 Feb;9(1):24-29. doi: 10.1007/s13730-019-00420-5. Epub 2019 Sep 21. PMID: 31542871 [PubMed – in process]

Inhibition of tissue-nonspecific alkaline phosphatase protects against medial arterial calcification and improves survival probability in the CKD-MBD mouse model.
Tani T, Fujiwara M, Orimo H, Shimizu A, Narisawa S, Pinkerton AB, Millán JL, Tsuruoka S.
J Pathol. 2020 Jan;250(1):30-41. doi: 10.1002/path.5346. Epub 2019 Nov 23. PMID: 31509234 [PubMed – in process]

Fate of full-house immunofluorescence staining in renal allograft: A case report.
Sawada A, Unagami K, Horita S, Kawanishi K, Okumi M, Taneda S, Ishida H, Hattori M, Tanabe K, Honda K, Uchida K, Shimizu A, Koike J, Nitta K, Nagashima Y.
Pathol Int. 2019 Nov;69(11):655-660. doi: 10.1111/pin.12847. Epub 2019 Sep 11. PMID: 31508868 [PubMed – in process]

Effect of H2 treatment in a mouse model of rheumatoid arthritis-associated interstitial lung disease.
Terasaki Y, Terasaki M, Kanazawa S, Kokuho N, Urushiyama H, Kajimoto Y, Kunugi S, Maruyama M, Akimoto T, Miura Y, Igarashi T, Ohsawa I, Shimizu A.
J Cell Mol Med. 2019 Oct;23(10):7043-7053. doi: 10.1111/jcmm.14603. Epub 2019 Aug 19. PMID: 31424157 [PubMed – in process]

Group 1 innate lymphoid cells are involved in the progression of experimental anti-glomerular basement membrane glomerulonephritis and are regulated by peroxisome proliferator-activated receptor α.
Okabayashi Y, Nagasaka S, Kanzaki G, Tsuboi N, Yokoo T, Shimizu A.
Kidney Int. 2019 Oct;96(4):942-956. doi: 10.1016/j.kint.2019.04.039. Epub 2019 May 22. PMID: 31402171 [PubMed – in process]

A case of membranous nephropathy diagnosed with lupus nephritis 11 years after onset.
Yamada T, Itagaki F, Aratani S, Kawasaki S, Terada K, Mugishima K, Kashiwagi T, Shimizu A, Tsuruoka S.
CEN Case Rep. 2019 Nov;8(4):301-307. doi: 10.1007/s13730-019-00412-5. Epub 2019 Aug 9. PMID: 31399881 [PubMed – in process]

Preparation of hybrid porcine thymus containing non-human primate thymic epithelial cells in miniature swine.
Sekijima M, Sahara H, Shimizu A, Iwanaga T, Murokawa T, Ariyoshi Y, Pomposelli T, Khosravi Maharlooei M, Sykes M, Yamada K.
Xenotransplantation. 2019 Nov;26(6):e12543. doi: 10.1111/xen.12543. Epub 2019 Jul 10. PMID: 31293016 [PubMed – in process]

The Protective Effects of Carbon Monoxide Against Hepatic Warm Ischemia-Reperfusion Injury in MHC-Inbred Miniature Swine.
Murokawa T, Sahara H, Sekijima M, Pomposelli T, Iwanaga T, Ichinari Y, Shimizu A, Yamada K.
J Gastrointest Surg. 2019 Jun 26. doi: 10.1007/s11605-019-04283-0. [Epub ahead of print] PMID: 31243716 [PubMed – as supplied by publisher]

Aging Vs. Hypertension: An Autopsy Study of Sclerotic Renal Histopathological Lesions in Adults With Normal Renal Function.
Okabayashi Y, Tsuboi N, Kanzaki G, Sasaki T, Haruhara K, Koike K, Takahashi H, Ikegami M, Shimizu A, Yokoo T.
Am J Hypertens. 2019 Jun 11;32(7):676-683. doi: 10.1093/ajh/hpz040. PMID: 31066457 [PubMed – in process]

Synergistic Impact of Diabetes and Hypertension on the Progression and Distribution of Glomerular Histopathological Lesions.
Sasaki T, Tsuboi N, Okabayashi Y, Haruhara K, Kanzaki G, Koike K, Takahashi H, Ikegami M, Shimizu A, Yokoo T.
Am J Hypertens. 2019 Aug 14;32(9):900-908. doi: 10.1093/ajh/hpz059. PMID: 31044221 [PubMed – in process]

Rapid progression to end-stage renal disease in a young female with mixed immunopathological features of lupus and ANCA-associated vasculitis.
Fukue R, Takeno M, Miyamoto D, Shirai Y, Nagahama K, Shimizu A, Kuwana M.
Int J Rheum Dis. 2019 May;22(5):956-958. doi: 10.1111/1756-185X.13573. Epub 2019 Apr 9. No abstract available. PMID: 30968562 [PubMed – indexed for MEDLINE]

IL-6-producing Renal Cell Carcinoma Causing Renal and Endocrine Paraneoplastic Syndromes.
Okada A, Higashihara T, Kusano T, Takemura K, Saigusa H, Maruno S, Matsumura M, Suzuki T, Shimizu A, Takano H.
Intern Med. 2019 Jul 1;58(13):1953-1960. doi: 10.2169/internalmedicine.2000-18. Epub 2019 Mar 28. PMID: 30918174 [PubMed – indexed for MEDLINE]

Monoclonal Immunoglobulin Deposition Disease and Related Diseases.
Kanzaki G, Okabayashi Y, Nagahama K, Ohashi R, Tsuboi N, Yokoo T, Shimizu A.
J Nippon Med Sch. 2019;86(1):2-9. doi: 10.1272/jnms.JNMS.2019_86-1. Review. PMID: 30918151 [PubMed – indexed for MEDLINE]

Naftopidil reduced the proliferation of lung fibroblasts and bleomycin-induced lung fibrosis in mice.
Urushiyama H, Terasaki Y, Nagasaka S, Kokuho N, Endo Y, Terasaki M, Kunugi S, Makita K, Isago H, Hosoki K, Souma K, Ishii T, Matsuzaki H, Hiraishi Y, Mikami Y, Noguchi S, Tamiya H, Mitani A, Yamauchi Y, Shimizu A, Nagase T.
J Cell Mol Med. 2019 May;23(5):3563-3571. doi: 10.1111/jcmm.14255. Epub 2019 Mar 15. PMID: 30873733 [PubMed – in process]

Analyses of alveolar epithelial injury via lipid-related stress in mammalian target of rapamycin inhibitor-induced lung disease.
Kokuho N, Terasaki Y, Kunugi S, Saito Y, Urushiyama H, Terasaki M, Hayashi H, Gemma A, Shimizu A.
Lab Invest. 2019 Jun;99(6):853-865. doi: 10.1038/s41374-018-0158-9. Epub 2019 Feb 6. PMID: 30728465 [PubMed – in process]

Molecular hydrogen attenuates gefitinib-induced exacerbation of naphthalene-evoked acute lung injury through a reduction in oxidative stress and inflammation.
Terasaki Y, Suzuki T, Tonaki K, Terasaki M, Kuwahara N, Ohsiro J, Iketani M, Takahashi M, Hamanoue M, Kajimoto Y, Hattori S, Kawaguchi H, Shimizu A, Ohsawa I.
Lab Invest. 2019 Jun;99(6):793-806. doi: 10.1038/s41374-019-0187-z. Epub 2019 Feb 1. PMID: 30710119 [PubMed – in process]

Pathologic glomerular characteristics and glomerular basement membrane alterations in biopsy-proven thin basement membrane nephropathy.
Kajimoto Y, Endo Y, Terasaki M, Kunugi S, Igarashi T, Mii A, Terasaki Y, Shimizu A.
Clin Exp Nephrol. 2019 May;23(5):638-649. doi: 10.1007/s10157-018-01687-1. Epub 2019 Jan 28. PMID: 30687875 [PubMed – indexed for MEDLINE]

Biopsy-based estimation of total nephron number in Japanese living kidney donors.
Sasaki T, Tsuboi N, Kanzaki G, Haruhara K, Okabayashi Y, Koike K, Kobayashi A, Yamamoto I, Ogura M, Hoy WE, Bertram JF, Shimizu A, Yokoo T.
Clin Exp Nephrol. 2019 May;23(5):629-637. doi: 10.1007/s10157-018-01686-2. Epub 2019 Jan 12. PMID: 30635748 [PubMed – indexed for MEDLINE]

Citrullinated histone H3 expression in anti-neutrophil cytoplasmic antibody-associated vasculitis in older Japanese autopsy patients.
Matsuda Y, Itabashi M, Tachibana Y, Sugihara T, Sakashita Y, Matsubara T, Murayama S, Yumura W, Shimizu A, Takei T, Arai T.
Geriatr Gerontol Int. 2019 Mar;19(3):259-264. doi: 10.1111/ggi.13596. Epub 2019 Jan 8. PMID: 30623538 [PubMed – indexed for MEDLINE]

A grading system that predicts the risk of dialysis induction in IgA nephropathy patients based on the combination of the clinical and histological severity.
Okonogi H, Kawamura T, Joh K, Koike K, Miyazaki Y, Ogura M, Tsuboi N, Hirano K, Matsushima M, Yokoo T, Horikoshi S, Suzuki Y, Yasuda T, Shirai S, Shibata T, Hattori M, Akioka Y, Katafuchi R, Hashiguchi A, Hisano S, Shimizu A, Kimura K, Maruyama S, Matsuo S, Tomino Y; Special IgA Nephropathy Study Group.
Clin Exp Nephrol. 2019 Jan;23(1):16-25. doi: 10.1007/s10157-018-1657-0. Epub 2018 Oct 26. Review. PMID: 30367317 [PubMed – indexed for MEDLINE]

Cholix toxin, an eukaryotic elongation factor 2 ADP-ribosyltransferase, interacts with Prohibitins and induces apoptosis with mitochondrial dysfunction in human hepatocytes.
Yahiro K, Ogura K, Terasaki Y, Satoh M, Miyagi S, Terasaki M, Yamasaki E, Moss J.
Cell Microbiol. 2019 Aug;21(8):e13033. doi: 10.1111/cmi.13033. Epub 2019 May 14. PMID: 31009148

Criteria for the diagnosis of idiopathic pleuroparenchymal fibroelastosis: A proposal.
Watanabe K, Ishii H, Kiyomi F, Terasaki Y, Hebisawa A, Kawabata Y, Johkoh T, Sakai F, Kondoh Y, Inoue Y, Azuma A, Suda T, Ogura T, Inase N, Homma S; Study Group on Diffuse Pulmonary Disorders, Scientific Research/Research on Intractable Diseases in Japan.
Respir Investig. 2019 Jul;57(4):312-320. doi: 10.1016/j.resinv.2019.02.007. Epub 2019 Apr 10. Review. PMID: 30981683

Organizing Pneumonia after Nivolumab Treatment in a Patient with Pathologically Proven Idiopathic Pulmonary Fibrosis.
Kashiwada T, Minegishi Y, Saito Y, Kato T, Atsumi K, Seike M, Kubota K, Terasaki Y, Gemma A.
J Nippon Med Sch. 2019;86(1):43-47. doi: 10.1272/jnms.JNMS.2019_86-8. PMID: 30918156 

Nationwide cloud-based integrated database of idiopathic interstitial pneumonias for multidisciplinary discussion.
Fujisawa T, Mori K, Mikamo M, Ohno T, Kataoka K, Sugimoto C, Kitamura H, Enomoto N, Egashira R, Sumikawa H, Iwasawa T, Matsushita S, Sugiura H, Hashisako M, Tanaka T, Terasaki Y, Kunugi S, Kitani M, Okuda R, Horiike Y, Enomoto Y, Yasui H, Hozumi H, Suzuki Y, Nakamura Y, Fukuoka J, Johkoh T, Kondoh Y, Ogura T, Inoue Y, Hasegawa Y, Inase N, Homma S, Suda T.
Eur Respir J. 2019 May 18;53(5). pii: 1802243. doi: 10.1183/13993003.02243-2018. Print 2019 May. PMID: 30880283

Spontaneous pulmonary hematoma with diffuse pulmonary ossification requiring emergency treatment: a case report.
Sonokawa T, Matsui T, Takegahara K, Inoue T, Kashiwada T, Terasaki Y, Usuda J.
Surg Case Rep. 2019 Feb 18;5(1):27. doi: 10.1186/s40792-019-0589-6. PMID: 30778690 

Anti-MDA5 antibody-positive rapidly progressive interstitial pneumonia without cutaneous manifestations.
Aoyama J, Hayashi H, Yajima C, Takoi H, Tanaka T, Kashiwada T, Kokuho N, Terasaki Y, Nishikawa A, Gono T, Kuwana M, Saito Y, Abe S, Seike M, Gemma A.
Respir Med Case Rep. 2019 Jan 14;26:193-196. doi: 10.1016/j.rmcr.2019.01.012. eCollection 2019.PMID: 30723666

Interstitial lung disease associated with nanoparticle albumin-bound paclitaxel treatment in patients with lung cancer.
Kashiwada T, Saito Y, Terasaki Y, Hisakane K, Takeuchi S, Sugano T, Miyanaga A, Noro R, Minegishi Y, Seike M, Kubota K, Gemma A.
Jpn J Clin Oncol. 2019 Feb 1;49(2):165-173. doi: 10.1093/jjco/hyy180. PMID: 30508192

2018年 

PPARα Agonist Suppresses Inflammation after Corneal Alkali Burn by Suppressing
Proinflammatory Cytokines, MCP-1, and Nuclear Translocation of NF-κB.
Nakano Y, Uchiyama M, Arima T, Nagasaka S, Igarashi T, Shimizu A, Takahashi H.
Molecules. 2018 Dec 29;24(1). pii: E114. doi: 10.3390/molecules24010114. PubMed PMID:
30597991; PubMed Central PMCID: PMC6337747.

Radiation-induced premature cellular senescence involved in glomerular diseases
in rats.
Aratani S, Tagawa M, Nagasaka S, Sakai Y, Shimizu A, Tsuruoka S.
Sci Rep. 2018 Nov 14;8(1):16812. doi: 10.1038/s41598-018-34893-8. PubMed
PMID: 30429495; PubMed Central PMCID: PMC6235850.

A Case of Hepatic Glomerulosclerosis with Monoclonal IgA1-κ Deposits.
Okabayashi Y, Tsuboi N, Nakaosa N, Haruhara K, Kanzaki G, Koike K, Shimizu A, Fukui A, Okonogi H, Miyazaki Y, Kawamura T, Ogura M, Shimizu A, Yokoo T.
Case Rep Nephrol. 2018 Oct 1;2018:4748357. doi: 10.1155/2018/4748357. eCollection 2018. PubMed PMID: 30364076; PubMed Central PMCID: PMC6188736.

Heterogeneous distribution of glomerular size in adult kidneys with normal renal function. Okabayashi Y, Kanzaki G, Tsuboi N, Haruhara K, Koike K, Ikegami M, Shimizu A, Yokoo T. Pathol Int. 2018 May 10. doi: 10.1111/pin.12681. [Epub ahead of print] PubMed PMID: 29749027.

Optimal conditions and the advantages of using laser microdissection and liquid chromatography tandem mass spectrometry for diagnosing renal amyloidosis.
Aoki M, Kang D, Katayama A, Kuwahara N, Nagasaka S, Endo Y, Terasaki M, Kunugi S, Terasaki Y, Shimizu A.
Clin Exp Nephrol. 2018 Aug;22(4):871-880. doi: 10.1007/s10157-018-1533-y. Epub 2018 Jan 25. PubMed PMID: 29372474.

A sarcomatoid localized malignant mesothelioma with osteosarcomatous elements.
Terasaki M, Terasaki Y, Takahashi M, Kokuho N, Kunugi S, Usuda J, Shimizu A.
Hum Pathol Case Rep. 2018 Nov;14:16-19.

Endometrioid carcinoma arising in a uterine adenomyoma.
Terasaki M, Terasaki Y, Kawase R, Shimizu A.
Hum Pathol Case Rep. 2018 Sept;13:24-26.

Molecular hydrogen attenuates gefitinib-induced exacerbation of naphthalene-evoked acute lung injury through a reduction in oxidative stress and inflammation.
Terasaki Y, Suzuki T, Tonaki K, Terasaki M, Kuwahara N, Ohsiro J, Iketani M, Takahashi M, Hamanoue M, Kajimoto Y, Hattori S, Kawaguchi H, Shimizu A, Ohsawa I.
Laboratory Investigation 2019, Feb;99:793-806

Citrullinated histone H3 expression in anti-neutrophil cytoplasmic antibody-associated vasculitis in older Japanese autopsy patients.
Matsuda Y, Itabashi M, Tachibana Y, Sugihara T, Sakashita Y, Matsubara T,
Murayama S, Yumura W, Shimizu A, Takei T, Arai T.
Geriatr Gerontol Int. 2019 Mar;19(3):259-264. doi:
10.1111/ggi.13596. Epub 2019 Jan 8. PubMed PMID: 30623538.

Special IgA Nephropathy Study Group. A grading system that predicts the risk of dialysis induction in IgA nephropathy patients based on the combination of the clinical and histological severity.
Okonogi H, Kawamura T, Joh K, Koike K, Miyazaki Y, Ogura M, Tsuboi N, Hirano K, Matsushima M, Yokoo T, Horikoshi S, Suzuki Y, Yasuda T, Shirai S, Shibata T, Hattori M, Akioka Y, Katafuchi R, Hashiguchi A, Hisano S, Shimizu A, Kimura K, Maruyama S, Matsuo S, Tomino Y;
Clin Exp Nephrol. 2019 Jan;23(1):16-25. doi: 10.1007/s10157-018-1657-0. Epub 2018 Oct 26. Review. PubMed PMID: 30367317; PubMed Central PMCID: PMC6344391. (査読有り)

Prognostic utility of atypical mitoses in patients with breast cancer: A comparative study
with Ki67 and phosphohistone H3.
Ohashi R, Namimatsu S, Sakatani T, Naito Z, Takei H, Shimizu A.
J Surg Oncol. 2018 Sep;118(3):557-567. doi:10.1002/jso.25152. Epub 2018 Aug 11. PubMed PMID: 30098295.

Proliferative glomerulonephritis with unusual microlamellar organized deposits related to monoclonal immunoglobulin G3 (IgG3) kappa.
Mii A, Shimizu A, Takada D, Tsuruoka S.
CEN Case Rep. 2018 Nov;7(2):320-324. doi:
10.1007/s13730-018-0351-0. Epub 2018 Jul 9. PubMed PMID: 29987665; PubMed Central PMCID: PMC6181896. (査読有り)

Palmitate deranges erythropoietin production via transcription factor ATF4 activation of unfolded protein response.
Anusornvongchai T, Nangaku M, Jao TM, Wu CH, Ishimoto Y, Maekawa H, Tanaka T, Shimizu A, Yamamoto M, Suzuki N, Sassa R, Inagi R.
Kidney Int. 2018 Sep;94(3):536-550. doi: 10.1016/j.kint.2018.03.011. Epub 2018 Jun 7. PubMed PMID: 29887316.

Renal Thrombotic Microangiopathy After Hematopoietic Stem Cell Transplantation:
Involvement of Chronic Graft-Versus-Host Disease.
Mii A, Shimizu A, Kaneko T, Nakayama K, Yamaguchi H, Tsuruoka S.
Kidney Int Rep. 2018 Jan 5;3(3):743-747. doi: 10.1016/j.ekir.2017.12.013. eCollection 2018 May. PubMed PMID: 29854984; PubMed Central PMCID: PMC5976851.

Assessment of renal fibrosis in murine diabetic nephropathy using quantitative magnetization transfer MRI.
Wang F, Katagiri D, Li K, Takahashi K, Wang S, Nagasaka S, Li H, Quarles CC, Zhang MZ, Shimizu A, Gore JC, Harris RC, Takahashi T.
Magn Reson Med. 2018 Dec;80(6):2655-2669. doi: 10.1002/mrm.27231. Epub 2018
May 30. PubMed PMID: 29845659; PubMed Central PMCID: PMC6269231.

Adipose-derived mesenchymal stem cells attenuate rejection in a rat lung transplantation model.
Watanabe H, Tsuchiya T, Shimoyama K, Shimizu A, Akita S, Yukawa H, Baba Y,
Nagayasu T.
J Surg Res. 2018 Jul;227:17-27. doi: 10.1016/j.jss.2018.01.016. Epub 2018 Mar 2. PubMed PMID: 29804850.

Evaluating the Feasibility of Isolated Pancreatic Perfusion for Chemotherapy Using Computed Tomography: An Experimental Study in Pig Models.
Murata S, Onozawa S, Yasui D, Ueda T, Sugihara F, Shimizu A, Suzuki K, Satake M.
Cardiovasc Intervent Radiol. 2018 Jul;41(7):1081-1088. doi: 10.1007/s00270-018-1943-y. Epub 2018 Mar 26. PubMed PMID: 29582129.

Breast carcinoma with osteoclast-like giant cells: A cytological-pathological correlation with a literature review.
Ohashi R, Hayama A, Matsubara M, Watarai Y, Sakatani T, Naito Z, Shimizu A.
Ann Diagn Pathol. 2018 Apr;33:1-5. doi: 10.1016/j.anndiagpath.2017.11.003. Epub 2017 Nov 9. Review. PubMed PMID: 29566940.

GalT-KO pig lungs are highly susceptible to acute vascular rejection in baboons, which may be mitigated by transgenic expression of hCD47 on porcine blood vessels.
Watanabe H, Sahara H, Nomura S, Tanabe T, Ekanayake-Alper DK, Boyd LK, Louras NJ, Asfour A, Danton MA, Ho SH, Arn SJ, Hawley RJ, Shimizu A, Nagayasu T, Ayares D, Lorber MI, Sykes M, Sachs DH, Yamada K.
Xenotransplantation. 2018 Sep;25(5):e12391. doi: 10.1111/xen.12391. Epub 2018 Mar 12. PubMed PMID: 29527745; PubMed Central PMCID: PMC6135720.

Immunomodulatory Effects of Fentanyl or Dexmedetomidine Hydrochloride Infusion After Allogeneic Heart Transplantation in Mice.
Chen W, Jin N, Lin Y, Villani V, Shimizu A, Zhao X, Lu F, Li C, Chen K, Lin Z, Qi Z.
Reg Anesth Pain Med. 2018 Jul;43(5):509-515. doi: 10.1097/AAP.0000000000000747. PubMed PMID: 29509567.

Importance of frequency and morphological characteristics of nodular diabetic glomerulosclerosis in diabetic nephropathy.
Yasuda F, Mii A, Morita M, Aoki M, Tagawa M, Aratani S, Kaneko T, Sakai Y, Shimizu A.
Hum Pathol. 2018 May;75:95-103. doi: 10.1016/j.humpath.2018.01.019. Epub 2018 Feb 2. PubMed PMID: 29408640.

Clinical features and pathogenesis of membranoproliferative glomerulonephritis: a nationwide analysis of the Japan renal biopsy registry from 2007 to 2015.
Nakagawa N, Hasebe N, Hattori M, Nagata M, Yokoyama H, Sato H, Sugiyama H, Shimizu A, Isaka Y, Maruyama S, Narita I.
Clin Exp Nephrol. 2018 Aug;22(4):797-807. doi: 10.1007/s10157-017-1513-7. Epub 2017 Dec 6. PubMed PMID: 29214407.

Organizing Pneumonia after Nivolumab Treatment in a Patient
with Pathologically Proven Idiopathic Pulmonary Fibrosis.
Kashiwada T, Minegishi Y, Saito Y, Kato T, Atsumi K, Seike M, Kubota K, Terasaki Y, Gemma A.
J Nippon Med Sch. 2019;86(1):43-47. doi: 10.1272/jnms.JNMS.2019_86-8. PubMed PMID: 30918156.

Spontaneous pulmonary hematoma with diffuse pulmonary ossification requiring
emergency treatment: a case report.
Sonokawa T, Matsui T, Takegahara K, Inoue T, Kashiwada T, Terasaki Y, Usuda J.
Surg Case Rep. 2019 Feb 18;5(1):27. doi:
10.1186/s40792-019-0589-6. PubMed PMID: 30778690; PubMed Central PMCID:
PMC6379494.

Anti-MDA5 antibody-positive rapidly progressive interstitial pneumonia without cutaneous manifestations.
Aoyama J, Hayashi H, Yajima C, Takoi H, Tanaka T, Kashiwada T, Kokuho N, Terasaki Y, Nishikawa A, Gono T, Kuwana M, Saito Y, Abe S, Seike M, Gemma A.
Respir Med Case Rep. 2019 Jan 14;26:193-196. doi:10.1016/j.rmcr.2019.01.012. eCollection 2019. PubMed PMID: 30723666; PubMed
Central PMCID: PMC6350262.

Rapidly Progressive Multiple Digital Gangrene and Diffuse Alveolar Damage in a Patient With Antisynthetase Antibody and Gastric Cancer.
Fukue R, Gono T, Hayashi H, Terasaki Y, Kuwana M.
J Clin Rheumatol. 2018 Dec 21. doi: 10.1097/RHU.0000000000000974. [Epub ahead of print] PubMed PMID: 30585991. (査読有り)

Interstitial lung disease associated with nanoparticle albumin-bound paclitaxel treatment in patients with lung cancer.
Kashiwada T, Saito Y, Terasaki Y, Hisakane K, Takeuchi S, Sugano T, Miyanaga A, Noro R, Minegishi Y, Seike M, Kubota K, Gemma A.
Jpn J Clin Oncol. 2019 Feb 1;49(2):165-173. doi: 10.1093/jjco/hyy180. PubMed PMID: 30508192.

A case of interstitial lung disease with alveolar hemorrhage induced by pembrolizumab.
Sugano T, Seike M, Noro R, Kaburaki S, Tozuka T, Takahashi A, Takano N, Tanaka T, Kashiwada T, Takeuchi S, Minegishi Y, Saito Y, Kubota K, Terasaki Y, Gemma A.
Onco Targets Ther. 2018 Sep 17;11:5879-5883. doi:10.2147/OTT.S169321. eCollection 2018. PubMed PMID: 30271171; PubMed Central PMCID: PMC6149979. (査読有り)

Pleuroparenchymal fibroelastosis diagnosed by multidisciplinary discussions in Japan.
Ishii H, Watanabe K, Kushima H, Baba T, Watanabe S, Yamada Y, Arai T, Tsushima K, Kondoh Y, Nakamura Y, Terasaki Y, Hebisawa A, Johkoh T, Sakai F, Takemura T, Kawabata Y, Ogura T; Tokyo Diffuse Lung Disease Study Group.
Respir Med. 2018 Aug;141:190-197. doi: 10.1016/j.rmed.2018.06.022. Epub 2018 Jun 27. PubMed PMID: 30053966.

Elotuzumab-induced interstitial lung disease: the first case report.
Tanaka T, Saito Y, Kokuho N, Tamura H, Terasaki Y, Seike M, Gemma A. Jpn J Clin Oncol. 2018 May 1;48(5):491-494. doi: 10.1093/jjco/hyy049. PubMed PMID: 29635485.

A case of anti-glomerular basement membrane antibody-positive systemic lupus erythematosus with pulmonary hemorrhage successfully treated at an early stage of the disease
Yamada T, Mugishima K, Higo S, Yoshida Y, Itagaki F, Yui S, Kashiwagi T, Endo Y, Shimizu A, Tsuruoka S.
Journal of Nippon Medical School 2018 Apr; 85(2):138-144

【間質性肺炎の診断 Up to Date】慢性経過の間質性肺炎に対するMDD診断 病理医の立場から
寺崎 泰弘, 國保 成暁, 寺崎 美佳, 功刀 しのぶ
臨床画像 34巻2号 p214-224 (2018)

2017年

Localized pulmonary crystal-storing histiocytosis complicating pulmonary mucosa-associated lymphoid tissue lymphoma presenting with multiple mass lesions. Kokuho N, Terasaki Y, Kunugi S, Onda N, Urushiyama H, Terasaki M, Hino M, Gemma A, Hatori T, Shimizu A. Hum Pathol 2017;65:180-186. DOI: 10.1016/j.humpath.2016.10.028.

Comparison of clinical and pathological features of lung lesions of systemic IgG4-related disease and idiopathic multicentric Castleman’s disease. Terasaki Y, Ikushima S, Matsui S, Hebisawa A, Ichimura Y, Izumi S, Ujita M, Arita M, Tomii K, Komase Y, Owan I, Kawamura T, Matsuzawa Y, Murakami M, Ishimoto H, Kimura H, Bando M, Nishimoto N, Kawabata Y, Fukuda Y, Ogura T, the Tokyo Diffuse Lung Disease Study Group. Histopathology. 2017;70(7):1114-1124. DOI: 10.1111/his.13186.

M-type phospholipase A2 receptor (PLA2R) glomerular staining in pediatric idiopathic membranous nephropathy. Kanda S, Horita S, Yanagihara T, Shimizu A, Hattori M. Pediatr Nephrol. 2017 Apr;32(4):713-717.

A novel case of renal pathergy reaction in a Behçet’s disease patient complicated by IgA vasculitis. Higashihara T, Okada A, Kusano T, Ishigaki K, Shimizu A, Takano H. BMC Nephrol. 2017 Jan 28;18(1):40.

Tolerance of Vascularized Islet-Kidney Transplants in Rhesus Monkeys. Pathiraja V, Villani V, Tasaki M, Matar AJ, Duran-Struuck R, Yamada R, Moran SG, Clayman ES, Hanekamp J, Shimizu A, Sachs DH, Huang CA, Yamada K Am J Transplant. 2017 Jan;17(1):91-102

Characterization of a murine model with arteritis induced by Nod1 ligand, FK565: a comparative study with a CAWS-induced model. Ohashi R, Fukazawa R, Watanabe M, Hashimoto K, Suzuki N, Nagi-Miura N, Ohno N, Shimizu A, Itoh Y Mod Rheumatol. 2017 Feb 2:1-19

TAZ contributes to pulmonary fibrosis by activating profibrotic functions of lung fibroblasts. Noguchi S, Saito A, Mikami Y, Urushiyama H, Horie M, Matsuzaki H, Takeshima H, Makita K, Miyashita N, Mitani A, Jo T, Yamauchi Y, Terasaki Y, Nagase T Sci Rep. 2017; 7: 42595

Follicular lymphoma presenting follicular papules in the skin: A case report. Ozaki S, Funasaka Y, Shimizu A, Kawarasaki M, Kanzaki A, Matano Y, Futagami A, Yamaguchi H, Sugisaki Y, Saeki H. J Dermatol. 2017 Jan;44(1):111-113.

Reproducibility for pathological prognostic parameters of the Oxford classification of IgA nephropathy: a Japanese cohort study of the Ministry of Health, Labor and Welfare. Hisano S, Joh K, Katafuchi R, Shimizu A, Hashiguchi N, Kawamura T, Matsuo S; IgA Nephropathy Study Group in Japan. Clin Exp Nephrol. 2017 Feb;21(1):92-96.

A novel case of renal pathergy reaction in a Behçet’s disease patient complicated by IgA vasculitis. Higashihara T, Okada A, Kusano T, Ishigaki K, Shimizu A, Takano H.  BMC Nephrol. 2017 Jan 28;18(1):40.

2016年

Pulmonary mucosa-associated lymphoid tissue lymphoma associated with pulmonary sarcoidosis: a case report and literature review. Kokuho N, Terasaki Y, Urushiyama H, Terasaki M, Kunugi S, Morimoto T, Azuma A, Usuda J, Gemma A, Eishi Y, Shimizu A. Hum Pathol. 2016;51:57-63.

Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type, with Primary Manifestation as an Upper Eyelid Swelling Kanzaki A, Funasaka Y, Nakamizo M, Shima A, Ryotokuji T, Dan K, Terasaki M, Sugisaki Y, Fukuda Y, Kawana S, Saeki H   J Nippon Medical School  2016;83:177-179.

Interstitial lung disease associated with amrubicin chemotherapy in patients with lung cancer: a single institutional study. Miura Y, Saito Y, Atsumi K, Takeuchi S, Miyanaga A, Mizutani H, Minegishi Y, Noro R, Seike M, Kunugi S, Kubota K, Gemma A. Jpn J Clin Oncol. 2016;46:674-680.

Interobserver Agreement of Usual Interstitial Pneumonia Diagnosis Correlated With Patient Outcome. Hashisako M, Tanaka T, Terasaki Y, Uekusa T, Achcar RD, Aswad BI, Bamefleh HS, Capelozzi VL, English JC, Fabro AT, Kataoka K, Hayashi T, Kondoh Y, Taniguchi H, Fukuoka J. Arch Pathol Lab Med. 2016;140(12):1375-1382.

Osteogenesis Imperfecta Associated with Dendriform Pulmonary Ossification. Morikawa M, Fukuda Y, Terasaki Y, Itoh H, Demura Y, Sasaki M, Imamura Y, Honjo C, Umeda Y, Anzai M, Ameshima S, Ishizaki T, Ishizuka T. Am J Respir Crit Care Med. 2016;193:460-461.

Clinical Course and Changes in High-Resolution Computed Tomography Findings in Patients with Idiopathic Pulmonary Fibrosis without Honeycombing.   Yamauchi H, Bando M, Baba T, Kataoka K, Yamada Y, Yamamoto H, Miyamoto A, Ikushima S, Johkoh T, Sakai F, Terasaki Y, Hebisawa A, Kawabata Y, Sugiyama Y, Ogura T. PLoS One. 2016;11(11): e0166168

Epstein-Barr Virus-positive T-cell lymphoproliferative disease following umbilical cord blood transplantation for acute myeloid leukemia. Yui S, Yamaguchi H, Imadome K, Arai A, Takahashi M, Ohashi R, Tamai H, Moriya K, Nakayama K, Shimizu A, Inokuchi K. J Nippon Med Sch. 2016;83(1):35-42.

Development of the Intestinal Transplantation Model With Major Histocompatibility Complex Inbred CLAWN Miniature Swine. Miura K, Sahara H, Waki S, Kawai A, Sekijima M, Kobayashi T, Zhang Z, Wakai T, Shimizu A, Yamada K.   Transplant Proc. 2016;48(4):1315-9.

Pathological sub-analysis of a multicenter randomized controlled trial of tonsillectomy combined with steroid pulse therapy versus steroid pulse monotherapy in patients with immunoglobulin A nephropathy. Katafuchi R, Kawamura T, Joh K, Hashiguchi A, Hisano S, Shimizu A, Miyazaki Y, Nagata M, Matsuo S; IgA nephropathy Study Group in Japan. Clin Exp Nephrol. 2016;20(2):244-52.

Presence of Citrullinated Histone H3-Positive Neutrophils in Microscopic Polyangiitis from the Early Phase: An Autopsy Proven Case. Matsuda Y, Hamayasu H, Seki A, Nonaka K, Wang T, Matsumoto T, Hamano Y, Sumikura H, Kumasaka T, Murayama S, Ishizu A, Shimizu A, Sugihara T, Arai T Pathol Int. 2016;66(8):466-71.

Hematopoietic Stem Cell Transplantation Nephropathy Associated with Chronic Graft-versus-Host Disease without Extrarenal Involvement.  Ishida R, Shimizu A, Kitani T, Nakata M, Ota N, Kado H, Shiotsu Y, Ishida M, Tamagaki K. Intern Med. 2016;55(19):2837-2842.

2015年

Uterine leiomyosarcoma with osteoclast-like giant cells associated with high expression of receptor activator of nuclear factor κB ligand Terasaki M, Terasaki Y, Yoneyama K, Kuwahara N, Wakamatsu K, Nagahama K, Kunugi S, Takeshita T, Shimizu A Hum Pathol. 2015;46:1679-1684.

Currently available useful immunohistochemical markers of renal pathology for the diagnosis of renal allograft rejection. Kanzaki G, Shimizu A   Nephrology (Carlton) 2015; 20 Suppl(2):9-15.

Endothelial cell injury in acute and chronic glomerular lesions in patients with IgA nephropathy Kusano T,Takano H, Kang D, Nagahama K, Aoki M, Morita M, Kaneko T, Tsuruoka S, Shimizu A. Hum Pathol.2015;49:135-44Glomerular endothelial cell injury and focal segmental glomerulosclerosis lesion in idiopathic membranous nephropathy. Morita M, Mii A, Shimizu A, Yasuda F, Shoji J, Masuda Y, Ohashi R, Nagahama K, Kaneko T, Tsuruoka S   PLoS One 2015; 10(4):e0116700.

IgA Nephropathy and Psoriatic Arthritis that Improved with Steroid Pulse Therapy and Mizoribinein Combination with Treatment for Chronic Tonsillitis and Epipharyngitis.   Kaneko T, Mii A, Fukui M, Nagahama K, Shimizu A, Tsuruoka S   Intern Med 2015;54(9):1085-90.

Role of α1 and α2 chains of type IV collagen in early fibrotic lesions of idiopathic interstitial pneumonias and migration of lung fibroblasts.   Urushiyama H, Terasaki Y, Nagasaka S, Terasaki M, Kunugi S, Nagase T, Fukuda Y, Shimizu A   Lab Invest 2015; 95(8):872-85.

Epicardial Catheter Ablation of Ventricular Tachycardia in No Entry Left Ventricle Mechanical Aortic and Mitral Valves Soejima K,  Nogami  A, Sekiguchi Y, Harada T , Satomi K, Hirose T, Ueda A, Miwa Y, Sato T, Nishio S, Shirai Y, Kowase S,  Murakoshi, N, Kunugi S, Murata H,  Nitta T, Aonuma K, Yoshino H. Circ Arrhythm Electrophysiol. 2015;8:381-389.

Effective Crizotinib schedule for an elderly patient with ALK rearranged non-small-cell lung cancer: a case report Fukuizumi A , Miyanaga A,Seike M, Kato Y, Nakamichi S, Chubachi K , Matsumoto M,  Noro R, Minegishi Y,  Kunugi S,  Kubota K and Gemma A BMC Research Notes 2015; 8:165

High incidence of xenogenic bone marrow engraftment in pig-to-baboon intra-bone bone marrow transplantation.  Tasaki M, Wamala I, Tena A, Villani V, Sekijima M, Pathiraja V, Wilkinson RA, Pratts S,Cormack TA, Clayman E, Arn JS, Shimizu A, Fishman JA, Sachs DH, Yamada K  Am J Transplant 2015; 15(4):974-83.

Glomerular damage in experimental proliferative glomerulonephritis under glomerular capillary hypertension. Wang P-R, Kitamura H, Shimizu A, Yamanaka N   Kidney Blood Press Res. 2015; 40(2):188-99.

Phospholipase A2 receptor positive membranous nephropathy long after living donor kidney transplantation between identical twins. Nephrology (Carlton) 2015; 20 Suppl(2):101-4.    Saito H, Hamasaki Y, Tojo A, Shintani Y, Shimizu A, Nangaku M

日本医科大学 解析人体病理学